My computer was having intermittent hard drive problems, and last week they got bad enough that I sent the Macbook Pro off for repair (free under warranty). Unfortunately browser support for SVG is still at best spotty and hasn’t improved much over the past couple of years, as far as I know. SVG will do interactive, but I’ve never got around to making the program interactive (and likely never will, now), so XPlasMap really makes much nicer maps. I also wrote a much more primitive (but still rather attractive) on-line plasmid-mapping program that is OS-independent: Savage Plasmids draws SVG maps and exports to Postscript.
XPlasMap only runs on Macs (though it’s written in Python/wxPython, which means that it should be a straightforward recompile to run on other OSes - but I only use Macs so haven’t tried).
Fixed: Genes with no name disrupt drawingĪssorted other bugfixes and UI improvements. Fixed: Show/Hide enzyme lost after save. Fixed: Contextual menus occasionally not responding. Fixed: Going from linear to circular, genes disappear. Fixed: Font preferences not always honored. Fixed: JPG and PNG exports use a large canvas with image only in one corner. Fixed: Intermittent Clear Recent Files bug. (Preference option) Common actions on a toolbar. “Plasmid comment” is now free-form text (can be moved and edited). The 0.96 release is mainly a bug-fix release there are preliminary versions of a couple of new features, with annotations being the main new feature. The class I region is highlighted in orange, class III region in green, and class II region in blue. This is the human genomic major histocompatibility region, imported directly from a GenBank file (3.7 million base pairs). Here’s a sample plasmid map, for Invitrogen’s pTracerCMV2 (click on the image for a larger version):Īnd here’s a sample of a linear DNA map (click for a larger version). xpmp files (which is simply an XML format I wanted to make sure that the information in the maps would remain accessible and in a non-proprietary format), or exported to PNG or JPG. It will also import from FastA files for both FastA and GenBank sequence it will map out restriction sites (slowly! –it’s no competition for specialized restriction mapping programs like EnzymeX or the venerable DNA Strider) and identify open reading frames (again, slowly). 
It also draws linear DNA maps and will draw maps by importing directly from GenBank files. XPlasMap is a DNA drawing program for MacOSX (MacOS10.4 and up only for this release a slightly older version runs on MacOS10.3 ) It draws plasmid maps with all the features you’d expect (genes, multiple cloning sites, restriction sites, and so on), pretty much interactive. XPlasMap 0.96 can be downloaded here, and the XPlasMap home page is here. I’ve released a new version of XPlasMap, version 0.96 (asymptotically approaching a non-beta release).
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